I am getting inconsistent and unexpected results when I try to use two Aardvark I2C/SPI Host Adapters cross-connected through the I2C/SPI Activity Board.

The I2C/SPI Activity Board must be powered on for the two Aardvark adapters to be cross connected properly. To power on your activity board, configure one of the Aardvark adapters to use target power through the Rosetta Language Bindings or the Control Center software.